Let’s talk about something I wish I’d known sooner as a cat parent: titer testing.
If you’re like me, you’ve probably heard this at the vet every year:
“Time for her annual vaccines!”
You nod. You pay. You don’t question it.
After all, we’re just trying to keep our cats healthy, right?
But here’s the thing nobody told me:
Your cat might not even need those yearly booster shots.
That’s where titer testing comes in.
In plain English: what is a titer test?
A titer test is a simple blood test that checks if your cat already has immunity to certain diseases.
It measures the number of antibodies your cat’s body already has.
If your cat’s titer levels are high enough, it means her immune system is still protected—and she doesn’t need another vaccine yet.
Think of it like this:
Your cat got a vaccine → her immune system made antibodies → the titer test checks if those antibodies are still ready to fight.
If they are? No booster needed.
If they aren’t? Then it might be time for another vaccine.
It’s basically a “let’s check first before we inject” approach.

Why does this matter?
We’ve been taught that yearly vaccines are required no matter what. But many cat parents (and some vets) don’t realize:
Once immunity is established, it can last for years—or even for life.
Research shows that some vaccines, like feline distemper (panleukopenia), can provide lifelong immunity after the initial kitten series and one-year booster.
And yet, many cats still get annual shots they may not even need.
Is it dangerous? Not necessarily. But here’s why many holistic cat parents choose titer testing instead:
- Avoid unnecessary exposure to vaccine chemicals like adjuvants and preservatives
- Lower the risk of side effects such as lethargy, fever, swelling, allergic reactions, or (rarely) vaccine-associated tumors
- Prevent overstimulation of the immune system, especially in seniors or immune-compromised cats
It’s not about being anti-vaccine. It’s about being intentional.
If your cat already has immunity, why expose her to more than she needs?
What diseases can you titer test for in cats?
Titer testing is most commonly used to check immunity for:
- Panleukopenia (feline distemper)
- Calicivirus
- Herpesvirus (rhinotracheitis)
These are the core feline vaccines.
Rabies titers exist, but in most places, rabies vaccines are legally required regardless of titer results.
How does titer testing work?
It’s simple:
- Your vet (or a titer testing service) draws a small blood sample.
- The blood is sent to a lab.
- You get results showing whether immunity is still protective.
If immunity is strong, no booster is needed.
If it’s low, a booster may be recommended.
Some vets will provide an exemption letter if titers show protection. Some holistic vets use titers as their main guide for vaccination schedules.
Do I have to titer test?
Nope. It’s completely optional.
Some people titer every few years. Some titer after the one-year booster. Others don’t titer at all.
But if you want to:
- Avoid unnecessary vaccines
- Be proactive about vaccine-related health risks
- Personalize care based on your cat’s actual immunity
…it’s a great tool.
How much does it cost?
Costs vary depending on location.
Some vets charge $80–$150 per titer. Some online services are more affordable.
Services like Hemopet and Nayked Pet allow you to mail in blood samples (drawn by your vet) for testing.
It’s often less expensive than you think, especially if spacing it out every few years instead of annually.
When should you consider titer testing?
You might want to consider it if:
- You have a senior cat and want to avoid unnecessary vaccines
- Your cat has had a vaccine reaction in the past
- You’re working with a holistic or integrative vet
- You’re concerned about overstimulating the immune system
- You want personalized data for peace of mind
Bottom line:
Titer testing lets you make vaccination decisions based on your cat’s actual immunity, not just a generic schedule.
It’s empowering. It’s personalized. And for many cat parents, it feels like the most respectful approach to their cat’s health.
Have you tried titer testing? Thinking about it? Feel free to share your experience in the comments.
FAQs
Are titer tests accurate for cats?
Yes. Titer tests are considered a reliable and accurate way to measure your cat’s immunity to core diseases like panleukopenia, calicivirus, and herpesvirus. They check the actual antibody levels in your cat’s blood, which gives you a clear picture of whether your cat is still protected or needs a booster. While no test is perfect, titers are widely used by holistic vets and many integrative clinics as an accurate guide for vaccination decisions.
How long do cat vaccines last?
Many cat vaccines last much longer than a year. Research shows that immunity for core vaccines, especially feline distemper (panleukopenia), can last several years or even for life after the initial kitten series and one-year booster. Instead of automatically vaccinating every year, titer testing helps you check whether your cat still has strong protection before giving another shot.
Do senior cats need vaccines every year?
No. Senior cats often have weaker immune systems, and unnecessary vaccines can put extra stress on their bodies. Many holistic and integrative vets recommend titer testing first, especially for older cats or those with chronic conditions. If your senior cat still has strong antibody levels, a booster usually isn’t needed.
Can I use titer test results instead of boosters?
In many cases, yes. If your cat’s titer test shows protective immunity, most vets agree a booster isn’t necessary. Some clinics will even provide a written exemption if your cat’s titers are strong.
What do titer test numbers mean?
Titer test numbers show how many antibodies your cat has for a specific disease. Higher numbers mean stronger immunity. Labs usually mark results as either “protective,” “low,” or “non-protective.”
- Protective = Your cat still has immunity → No booster needed
- Borderline or Low = Immunity may be fading → Your vet may recommend a booster
- Non-protective = No measurable immunity → Booster is usually recommended
Your vet or the lab report will interpret the numbers so you know exactly what each value means for your cat.
